In vitro bone marrow toxicity of nucleoside analogs against human immunodeficiency virus
Open Access
- 1 April 1989
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 33 (4) , 576-579
- https://doi.org/10.1128/aac.33.4.576
Abstract
3'-Azido-2',3'-dideoxythymidine is known to cause severe anemia and neutropenia. Although these are rare for 2',3'-dideoxycytidine, it frequently impairs thrombocytogenesis. These differential myelossuppressive features correlated well with the in vitro toxicities of the drugs for a megakaryoblastic cell line and for colony formation of erythroid and granulocytic cells.This publication has 14 references indexed in Scilit:
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