Complement-Mediated Bactericidal System: Evidence for a New Pathway of Complement Action
- 17 October 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 190 (4211) , 278-280
- https://doi.org/10.1126/science.1101380
Abstract
The early components of human complement (C1, C4, and C2) plus certain serum euglobulins will kill pathogenic strains of Shigella sonnei . Serum from patients with hereditary C3 deficiencies and specific antiserums to C3, C5, and C6 were utilized to demonstrate the absence of requirements for late-acting complement components in this unusual bactericidal system.Keywords
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