Initiation and Promotion Activity of Certain Polynuclear Hydrocarbons23
- 1 December 1959
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 23 (6) , 1383-1387
- https://doi.org/10.1093/jnci/23.6.1383
Abstract
When tested as initiators of carcinogenesis per 3.5 cm.2 of mouse skin, 1 µg. of 7,12-dimethylbenz[a]anthracene was very potent, 0.1 µg. of this hydrocarbon had marginal activity, 0.9 µg. of benz[a]anthracene was a little more active than 0.1 µg. of 7,12-dimethylbenz[a]anthracene, and 9-methylanthracene was inactive. Both benz[a]anthracene and 9-methylanthracene were inactive as promoters of carcinogenesis.Keywords
This publication has 5 references indexed in Scilit:
- ON THE ROLE OF CROTON OIL IN TUMOR FORMATION1957
- METABOLIC AND CARCINOGENIC STUDIES WITH 9,10-DIMETHYL-1,2-BENZANTHRACENE1956
- THE INTERACTION OF CARCINOGENIC HYDROCARBONS WITH TISSUE CONSTITUENTS .4. A QUANTITATIVE STUDY OF THE BINDING TO SKIN PROTEINS OF SEVERAL C-14-LABELED HYDROCARBONS1956
- SPECTROMETRIC STUDIES OF THE PERSISTENCE OF FLUORESCENT DERIVATIVES OF CARCINOGENS IN MICE1954
- INHIBITION OF 9,10-DIMETHYL-1,2-BENZANTHRACENE SKIN CARCINOGENESIS IN MICE BY POLYCYCLIC HYDROCARBONS1951