B-cell precursors specific to sheep erythrocytes. Estimation of frequency in a specific helper assay.
Open Access
- 1 December 1978
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 148 (6) , 1612-1619
- https://doi.org/10.1084/jem.148.6.1612
Abstract
A sensitive, specific, and reproducible in vitro helper assay is described which is suited to limiting dilution analysis of murine B cells. 1 in about 3,000 syngeneic splenic B cells can be induced to form plaque-forming cells (PFC) to sheep erythrocytes in this system. The induction of PFC is absolutely dependent on antigen and specific helper T cells.This publication has 11 references indexed in Scilit:
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