A METHOD FOR THE SIMULTANEOUS RECORDING OF FOCAL CEREBRAL BLOOD FLOW, pH, ELECTRICAL ACTIVITY AND BLOOD PRESSURE

Abstract
A standard set of high gain condenser-coupled amplifiers and ink-writing recorders is used for the measurement of physiological variables expressed or translated into D.C. voltage changes. Focal cortical pH, blood flow, and electrical activity, as well as systemic blood pressure, are used as examples, with illustrations of the effect of adrenaline and hyperventilation. The essential principle consists of a series of quiet mechanical contacts which short circuit the input of the amplifiers at a rate of about 16/sec. D.C. voltage changes of less than 5 microvolts can be measured from a quiet base line.

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