Magnetizable Solid-phase Supports for Purification of Nucleic Acids
- 1 February 1996
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 48 (2) , 147-149
- https://doi.org/10.1111/j.2042-7158.1996.tb07113.x
Abstract
A simple, small scale non-hazardous procedure for the production of magnetizable solid-phase support (MSPS) beads has been developed based on the extrusion of agarose/iron oxide mixtures. The MSPS beads were derivatized using various amine ligands. Derivatized MSPS beads were used to adsorb nucleic acids from aqueous solution and to separate RNA/DNA mixtures.Keywords
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