EFFECT OF REDUCED EXTRACELLULAR SODIUM CONCENTRATION ON THE FUNCTION OF ADRENAL ZONA GLOMERULOSA: STUDIES ON ISOLATED GLOMERULOSA CELLS FROM THE RAT

1 June 1981

journal article
research article
Published by Bioscientifica in Journal of Endocrinology

Vol. 89 (3) , 417-421
https://doi.org/10.1677/joe.0.0890417

Abstract

Aldosterone production by isolated adrenal glomerulosa cells from the rat was estimated in the presence of varying concentrations of sodium ion. The reduction of sodium concentration by 5–20 mmol/l, with or without osmotic changes, did not influence the rate of aldosterone production. Aldosterone response to angiotensin II was not modified by varying the sodium concentration.

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