Effects of Antidepressant Medication on Morbidity and Mortality in Depressed Patients After Myocardial Infarction
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Open Access
- 1 July 2005
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 62 (7) , 792-798
- https://doi.org/10.1001/archpsyc.62.7.792
Abstract
Cardiovascular disease (CVD) is the leading cause of death, major morbidity, and disability among men and women in the United States, with an estimated 6 million people having symptomatic coronary heart disease.1 The prevalence of major depression is about 20% in patients with a recent myocardial infarction (MI)2-4 and about the same for minor depression.3 In patients who experience an acute MI (AMI), depression is a risk factor for recurrent nonfatal infarction and cardiac mortality, independent of cardiac disease severity.5,6Keywords
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