Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study

Open Access

17 January 2006

journal article
Published by CMA Impact Inc. in CMAJ : Canadian Medical Association Journal

Vol. 174 (2) , 169-174
https://doi.org/10.1503/cmaj.050748

Abstract

Background: Over the past 30 years, the relation between use of sulfonylureas to treat type 2 diabetes and the risk of cardiovascular events has been vigorously debated. The purpose of this study was to determine if the risk of death changes with level of exposure to sulfonylurea drugs.

Keywords

This publication has 27 references indexed in Scilit:

Sulfonylurea K _ATP Blockade in Type II Diabetes and Preconditioning in Cardiovascular Disease
Circulation, 1996
Sulphonylurea treatment of NIDDM patients with cardiovascular disease: a mixed blessing?
Diabetologia, 1996
Sulfonylureas in NIDDM
Diabetes Care, 1992
A chronic disease score from automated pharmacy data
Journal of Clinical Epidemiology, 1992
Molecular mechanisms of action of glyburide on the beta cell
The American Journal of Medicine, 1990
PREVALENCE OF ANGINA AS ASSESSED BY A SURVEY OF PRESCRIPTIONS FOR NITRATES
The Lancet, 1988
Compliance in hypertension: facts and concepts.
1985
Process versus outcome in hypertension: a positive result.
Circulation, 1982
A Summary of Criticisms of the Findings and Conclusions of the University Group Diabetes Program (UGDP)
Diabetes, 1972
The University Group Diabetes Program. A further statistical analysis of the mortality findings
JAMA, 1971