24 HOUR PROFILE OF 18-HYDROXY-11-DEOXYCORTICOSTERONE IN NORMAL SUPINE MAN: RELATIONSHIP WITH CORTISOL AND ALDOSTERONE
- 1 May 1978
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 8 (5) , 367-372
- https://doi.org/10.1111/j.1365-2265.1978.tb02170.x
Abstract
Daily profiles of plasma 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) were studied in 4 normal supine men on a normal Na intake. Blood was taken every hour from 01.00 to 24.00 hours. Plasma cortisol (F) and aldosterone (A) were determined hourly for comparative studies. 18-OH-DOC fluctuated considerably during the 24 h period of investigation, the highest values being found during the early morning hours in synchrony with F. The episodic secretions of 18-OH-DOC were also significantly correlated with those of A, which in turn paralleled those of F. ACTH, plays a definite role in the regulation of 18-OH-DOC in normal supine men on a normal Na diet.This publication has 12 references indexed in Scilit:
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