GnRH Interaction with Anterior Pituitary. II. Cyclic AMP as an Intracellular Mediator in the GnRH Activated Gonadotroph1
- 1 October 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 21 (3) , 735-747
- https://doi.org/10.1095/biolreprod21.3.735
Abstract
Suspensions of ovine anterior pituitary cells were prepared by sequential incubation with hyaluronidase-collagenase and trypsin. After an 18 h culture in suspension, cells were used 1) as a bioassay system to evaluate the LH releasing potency of GnRH and analogs of GnRH and 2) to investigate the role of cAMP as an intracellular second messenger for GnRH-induced release of LH.This publication has 26 references indexed in Scilit:
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