Tumor Inhibiting Properties of Stereoisomeric [1,2‐Bis(3‐hydroxyphenyl)ethylenediamine]dichloroplatinum(II)‐Complexes, Part I: Synthesis
- 1 January 1989
- journal article
- research article
- Published by Wiley in Archiv der Pharmazie
- Vol. 322 (1) , 25-29
- https://doi.org/10.1002/ardp.19893220107
Abstract
The synthesis of the stereoisomeric 1,2‐bis(3‐hydroxyphenyl)ethylenediamines (1–4) from meso‐1,2‐bis(2‐hydroxyphenyl)ethylenediamine and 3‐methoxybenzaldehyde by a diaza‐Cope‐rearrangement and subsequent ether cleavage with BBr3 and their conversion into the [1,2‐bis(3‐hydroxyphenyl)ethylenediamine]dichloroplatinum(II)‐complexes with K2PtCl4 (1‐PtCl2–4‐PtCl2) is described.This publication has 4 references indexed in Scilit:
- Zur Antitumorwirkung o‐substituierter [1,2‐Bis(4‐hydroxyphenyl)‐ethylendiamin]dichloroplatin(II)‐Komplexe und ihrer MethyletherArchiv der Pharmazie, 1988
- Dichloro[1,2-bis(4-hydroxyphenyl)ethylenediamine]platinum(II) complexes: an approach to develop compounds with a specific effect on the hormone-dependent mammary carcinomaJournal of Medicinal Chemistry, 1984
- Die Diaza‐ Cope ‐UmlagerungEuropean Journal of Inorganic Chemistry, 1976
- Configuration absolue de la (-) stilbenediamineTetrahedron Letters, 1974