Pain perception and endorphine levels in cerebrospinal fluid
- 1 December 1978
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 5 (4) , 359-365
- https://doi.org/10.1016/0304-3959(78)90004-0
Abstract
In 45 consecutive patients with chronic pain syndromes endorphins, fraction I of the cerebrospinal fluid and pain measures by means of electric stimulation via saline electrodes were investigated. In patients with high levels of fraction I (above median) pain threshold, PT and tolerance level, TL, in condition C (continuous stimulation increase) were found to be significantly higher than in patients with low levels of fraction I (below median). The results indicate that the endorphins are one of the physiological factors that contribute to the pain threshold and the tolerance level.Keywords
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