Asymmetric hydrogenation with antibody-achiral rhodium complex
- 25 August 2006
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 4 (19) , 3571-3573
- https://doi.org/10.1039/b609242j
Abstract
Monoclonal antibodies have been elicited against an achiral rhodium complex and this complex was used in the presence of a resultant antibody, 1G8, for the catalytic hydrogenation of 2-acetamidoacrylic acid to produce N-acetyl-L-alanine in high (>98%) enantiomeric excess.Keywords
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