SODOKU TREATMENT IN PARESIS
- 9 March 1929
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 92 (10) , 772-773
- https://doi.org/10.1001/jama.1929.02700360010003
Abstract
The first use ofSpirochaeta morsus-muris, the rat bite fever organism, in the treatment of paresis in this country was made by Dr. H. C. Solomon1of Boston. With this treatment he hoped to eliminate most of the disadvantages of the malaria treatment. He found the treatment comparatively simple and harmless; the infection was of a benign character and easily controlled by arsphenamine. In addition, rat bite fever was less severe on the patient than malaria and could be used on patients who were immune to the latter. We found that rat bite fever could not be transmitted from man to man. The spirillum of rat bite fever lives in the blood of rats and mice without producing symptoms of illness. Guinea-pigs infected withSpirochaeta morsus-murisshow symptoms similar to those in man. The encouraging report on this method by Solomon and his co-workers stimulated us to try thisKeywords
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