The Immunogenicity of Hapten-Polylysine Conjugates
Open Access
- 1 February 1965
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 94 (2) , 289-294
- https://doi.org/10.4049/jimmunol.94.2.289
Abstract
Summary: The immunogenicity of L and D polylysines substituted with penicilloyl, dinitrophenyl and tosyl groups has been evaluated in random-bred Hartley strain guinea pigs. The L polylysine derivatives produced an immunologic response in about 20% of animals. Of a total of 106 guinea pigs immunized with D polylysine conjugates, in no instance was there evidence for antibody formation.Keywords
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