Tissue response to percutaneous implants in rabbits

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Abstract
This study reports on certain aspects of wound‐healing around percutaneous implants. Plasma‐sprayed and dense hydroxylapatite, titanium, and carbon test implants were inserted into the tibia and the cranium of 12 rabbits. Four and 8 months after insertion, the animals were sacrificed and the implants with their surrounding tissues were processed histologically. Light‐ and transmission electron microscopic investigations were performed. It is found that direct and indirect boneanchoring favors the longevity of percutaneous implants. No differences in tissue reaction between the various implant materials were observed.

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