[The efficacy of established, systemically active trichomonacidal agents in the infection model tri-chomonas vaginalis/rat (author's transl)].

  • 1 January 1977
    • journal article
    • abstracts
    • Vol. 27  (3) , 638-9
Abstract
Experimental chemotherapeutical studies were carried out with metronidazole, tinidazole, nitrimidazine and ornidazole in rats infected with Trichomonas vaginalis intravaginally. All compounds tested showed a systemic trichomonacidal activity within rather a narrow dosage range after three oral doses and also after a single dose, i.e., 1.4-3.0 mg/kg and 7.7-15.9 mg/kg body weight (DC50), respectively.

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