Can Routine Clinical Markers Be Used Longitudinally to Monitor Antiretroviral Therapy Success in Resource‐Limited Settings?
Open Access
- 1 January 2007
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 44 (1) , 135-138
- https://doi.org/10.1086/510072
Abstract
Although routine clinical markers are used routinely to determine the stage of human immunodeficiency virus (HIV) disease, their use in monitoring response to antiretroviral therapy is poorly defined. Selected clinical markers were evaluated for their ability to predict first-line antiretroviral therapy success. No clinically meaningful variables were identified that predicted virologic or immunological success, implying that the CD4+ cell count and HIV type 1 RNA level data are required for optimal management of antiretroviral therapy.Keywords
This publication has 9 references indexed in Scilit:
- Changes in Total Lymphocyte Count as a Surrogate for Changes in CD4 Count Following Initiation of HAART: Implications for Monitoring in Resource-Limited SettingsJAIDS Journal of Acquired Immune Deficiency Syndromes, 2004
- Use of Total Lymphocyte Count for Monitoring Response to Antiretroviral TherapyClinical Infectious Diseases, 2004
- Total lymphocyte count and hemoglobin combined in an algorithm to initiate the use of highly active antiretroviral therapy in resource-limited settingsAIDS, 2003
- Usefulness of total lymphocyte count in monitoring highly active antiretroviral therapy in resource-limited settingsAIDS, 2003
- Total Lymphocyte Count (TLC) Is a Useful Tool for the Timing of Opportunistic Infection Prophylaxis in India and Other Resource-Constrained CountriesJAIDS Journal of Acquired Immune Deficiency Syndromes, 2002
- Cheaper HIV drugs for poor nations bring a new challenge: monitoring treatment.JAMA, 2002
- CD4+ T-Lymphocyte Counts in HIV InfectionJAIDS Journal of Acquired Immune Deficiency Syndromes, 1997
- CD4 and total lymphocyte counts as predictors of HIV disease progressionQJM: An International Journal of Medicine, 1996
- Total lymphocyte count as a predictor of absolute CD4+ count and CD4+ percentage in HIV-infected personsPublished by American Medical Association (AMA) ,1993