Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL‐37
Top Cited Papers
Open Access
- 3 October 2002
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 46 (1) , 157-168
- https://doi.org/10.1046/j.1365-2958.2002.03146.x
Abstract
Effectors of the innate immune system, the anti‐bacterial peptides, have pivotal roles in preventing infection at epithelial surfaces. Here we show that proteinases of the significant human pathogens...Keywords
This publication has 46 references indexed in Scilit:
- Differential Proteinase Expression by Pseudomonas aeruginosa Derived from Chronic Leg UlcersActa Dermato-Venereologica, 2001
- Innate antimicrobial peptide protects the skin from invasive bacterial infectionNature, 2001
- Cutaneous Injury Induces the Release of Cathelicidin Anti-Microbial Peptides Active Against Group A StreptococcusJournal of Investigative Dermatology, 2001
- Substrate Specificity in the Highly Heterogeneous M4 Peptidase Family Is Determined by a Small Subset of Amino AcidsJournal of Biological Chemistry, 2000
- Degradation of Antiproteinases, Complement and Fibronectin in Chronic Leg Ulcers: Investigative ReportActa Dermato-Venereologica, 2000
- Bacterial Phosphorylcholine Decreases Susceptibility to the Antimicrobial Peptide LL-37/hCAP18 Expressed in the Upper Respiratory TractInfection and Immunity, 2000
- Human beta-defensin-2The International Journal of Biochemistry & Cell Biology, 1999
- Dermatan Sulfate Released after Injury Is a Potent Promoter of Fibroblast Growth Factor-2 FunctionJournal of Biological Chemistry, 1998
- Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domainFEBS Letters, 1995
- Defensins in granules of phagocytic and non-phagocytic cellsTrends in Cell Biology, 1995