Activation of human complement system in paracoccidioidomycosis
- 1 January 1992
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 30 (4) , 317-321
- https://doi.org/10.1080/02681219280000411
Abstract
Plasma samples of 14 patients with paracoccidioidomycosis were analysed for components that represent activation of the complement system. Most patients (12/13) showed significant titres of complement-fixing antibodies and 14/14 had increased C4d/C4 ratios. There was no conclusive correlation between these two immunological indices, however. Factor B values of patients were similar to normal donors and fragment Ba was not detected in any of the patients. These results indicate a classical complement pathway activation in the plasma of patients with paracoccidioidomycosis.Keywords
This publication has 13 references indexed in Scilit:
- Complement activation in Brazilian pemphigus foliaceusClinical and Experimental Dermatology, 1989
- Complement in the Pathophysiology of Human DiseaseNew England Journal of Medicine, 1987
- Correlation between cell-mediated immunity and clinical forms of paracoccidioidomycosisTransactions of the Royal Society of Tropical Medicine and Hygiene, 1985
- Serology of paracoccidioidomycosis. II. Correlation between class-specific antibodies and clinical forms of the diseaseTransactions of the Royal Society of Tropical Medicine and Hygiene, 1984
- T-cell dysfunction and hyperimmunoglobulinemia E in paracoccidioidomycosisMycopathologia, 1982
- The activation of the complement system by Paracoccidioides brasiliensis in vitro: Its opsonic effect and possible significance for an in vivo model of infectionClinical Immunology and Immunopathology, 1979
- Immune responses in paracoccidioidomycosisMedical Mycology, 1978
- In vivo and in vitro evaluation of cell-mediated immunity in patients with paracoccidioidomycosisCellular Immunology, 1976
- A Familial Deficiency of the Phagocytosis-Enhancing Activity of Serum Related to a Dysfunction of the Fifth Component of Complement (C5)New England Journal of Medicine, 1970
- Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodiesAnalytical Biochemistry, 1966