ACUTE MASSIVE DIGITOXIN POISONING: REPORT OF A CASE AND REVIEW OF THE LITERATURE

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Abstract
Paroxysmal tachycardia with AV block was observed in a 61-year-old patient without previous heart disease who ingested 7.5 mg of digitoxin with suicidal intent. The usual manifestations of profound nausea and vomiting were observed, as well as a toxic delirium and an excessive renal excretion of nitrogen. Fluid balance studies and metobolic observations are reported. Although death occurred, it was on the 13th day and was due to bronchopneumonia and uremia rather than to cardiac effects. No significant myocardial changes were observed at autopsy. The mortality rate determined in a review of cases of acute massive digitoxin poisoning was 13%.

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