Synthesis of erivanin and 1-epierivanin from 1-(α)-santonin

Abstract
Synthesis of erivanin (2) along with its 1-epimer (17) is reported starting from 1-(α)-santonin, the crucial step in the synthesis being the successful application of Mitsunobu epimerisation procedure on a eudesmanic alcohol (15a) in bringing about inversion of configuration at C-1.

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