The Kinetics of Degradation of Ethacrynic Acid in Aqueous Solution
- 1 January 1983
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 9 (1-2) , 35-41
- https://doi.org/10.3109/03639048309048543
Abstract
The degradation of Ethacrynic Acid has been investigated as a function of temperature and concentration. Degradation produced a dimer, the concentrations being measured using an HPLC analysis. Degradation data were fitted to the Arrhenius equation using a least squares regression analysis. Data were fitted separately for each temperature and simultaneously for all temperatures. Arrhenius parameters were calculated. A statistical assessment of the influence of experimental design on the estimation of Arrhenius parameters has been made.Keywords
This publication has 1 reference indexed in Scilit:
- Polarographic Determination of Ethacrynic AcidJournal of Pharmaceutical Sciences, 1971