Science, medicine, and the future: Islet and stem cell transplantation for treating diabetes
- 6 January 2001
- Vol. 322 (7277) , 29-32
- https://doi.org/10.1136/bmj.322.7277.29
Abstract
Methods Our article is based on information from the following core references: the international islet transplant registry; recently published articles describing improvements in islet cell transplantation, reporting treatment of diabetes in animal models with islet cells grown in vitro, and describing novel molecular mechanisms in pancreatic endocrine development (including our own recent work); papers in embryonic and adult stem cell research that have had a major influence on our thinking; and the seminal work from the Roslin Institute and other groups on nuclear transfer. Footnotes Competing interests The authors are employed by and have financial interests in Novo Nordisk A/S, which manufactures insulin.This publication has 14 references indexed in Scilit:
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- In vitro cultivation of human islets from expanded ductal tissueProceedings of the National Academy of Sciences, 2000
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- Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cellsNature Medicine, 2000
- Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.1998
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