NMR screening techniques in drug discovery and drug design
- 22 November 2002
- journal article
- review article
- Published by Elsevier in Progress in Nuclear Magnetic Resonance Spectroscopy
- Vol. 41 (3-4) , 187-231
- https://doi.org/10.1016/s0079-6565(02)00049-3
Abstract
No abstract availableKeywords
This publication has 133 references indexed in Scilit:
- Hydrogen Bonds in RNA Base Pairs Investigated by Cross-Correlated Relaxation of Multiple-Quantum Coherence in NMRChemphyschem, 2001
- Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain 1 1Edited by F. E. CohenJournal of Molecular Biology, 1999
- Water molecules in the binding cavity of intestinal fatty acid binding protein: dynamic characterization by Water17O and 2H magnetic relaxation dispersionJournal of Molecular Biology, 1999
- Comparison of the Bioactive Conformations of Sialyl LewisX and a Potent Sialyl LewisX MimicAngewandte Chemie International Edition in English, 1997
- Analysis of biofluids and chemical mixtures in non-deuterated solvents with1H diffusion-weighted PFG phase-sensitive double-quantum NMR spectroscopyNMR in Biomedicine, 1997
- Residence times of the buried water molecules in bovine pancreatic trypsin inhibitor and its G36S mutantBiochemistry, 1995
- Protein Hydration Viewed by High-Resolution NMR Spectroscopy: Implications for Magnetic Resonance Image ContrastAccounts of Chemical Research, 1995
- Determination of absolute values of dipolar cross‐relaxation rates for ligands bound to macromolecules using double‐selective T1Magnetic Resonance in Chemistry, 1992
- Relaxation in the rotating frame in liquidsProgress in Nuclear Magnetic Resonance Spectroscopy, 1992
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973