Influence of Drugs on Clinical Chemical Data for Serum Glucose, Investigated with the Automated Glucose Oxidase-Perid Method

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Abstract
Drugs (50), applied in therapy of internal diseases, were investigated for their effect on the clinical chemical determination of serum glucose by the automated GOD[glucose oxidase]-Perid method. A statistically significant depression of the reported glucose value was caused by 7 drugs containing the pyrazolone group and its derivates (Baralgin, Butazolidin, Analgin, Novalgetol, Analgocain, Irgapyrin, aminopyrine) P < 0.001; P < 0.01. The influence depends on the quantity of drug and on the time interval between loading and glucose analysis.

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