Long-Term Stable Correction of Low-Density Lipoprotein Receptor–Deficient Mice With a Helper-Dependent Adenoviral Vector Expressing the Very Low-Density Lipoprotein Receptor
- 6 March 2001
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 103 (9) , 1274-1281
- https://doi.org/10.1161/01.cir.103.9.1274
Abstract
Background—Familial hypercholesterolemia (FH) that results from LDL receptor (LDLR) deficiency affects ≈1 in 500 persons in the heterozygous state and ≈1 in 1 million persons in the homozygous stat...Keywords
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