Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced cholesterol accumulation.

This publication has 24 references indexed in Scilit:

• Unmodified low density lipoprotein causes cholesteryl ester accumulation in J774 macrophages.
  Proceedings of the National Academy of Sciences, 1985
• Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells.
  The Journal of cell biology, 1983
• LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis
  Annual Review of Biochemistry, 1983
• Esterification of cholesterol and 25-hydroxycholesterol by rat liver microsomes
  Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
• [19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
  Published by Elsevier ,1983
• Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
  Proceedings of the National Academy of Sciences, 1979
• Inhibition of cholesteryl ester formation in human fibroblasts by an analogue of 7-ketocholesterol and by progesterone
  Proceedings of the National Academy of Sciences, 1978
• The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis
  Annual Review of Biochemistry, 1977
• Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.
  Proceedings of the National Academy of Sciences, 1976
• Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts.
  Journal of Clinical Investigation, 1975