EXPRESSION OF CYSTIC-FIBROSIS GENOTYPE IN CULTURED SOMATIC-CELLS

  • 1 January 1976
    • journal article
    • review article
    • Vol. 34  (1) , 135-150
Abstract
Observations on the characteristics of the [human] cell with the cystic fibrosis (CF) genotype in culture are reviewed. Although numerous and diverse abnormalities were described, none were specific for the CF gene. The relevance of each of these abnormalities to the clinical syndrome known as CF is discussed, emphasizing that the value thus far of such cell culture research is to learn how the CF gene influences cellular function.

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