Acute pancreatitis after renal transplantation
- 1 November 1989
- journal article
- case report
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 76 (11) , 1132-1135
- https://doi.org/10.1002/bjs.1800761108
Abstract
Post-transplantation pancreatitis is an infrequent complication with a high risk of mortality. In a 7-year period, there were five patients who had documented pancreatitis out of a total of 488 renal homograft recipients, an incidence of 1 per cent. Two cases occurred in patients with an orthotopic transplant, one of them as a result of surgical injury of the pancreas and the other as a consequence of cytomegalovirus infection. The third case was an acute pancreatitis of hypercalcaemic origin, the fourth patient developed postoperative pancreatitis and acute acalculous cholecystitis, and the fifth had acute pancreatitis and sepsis associated with cytomegalovirus infection. Three patients died as a direct result of the complication. The mean incidence and mean mortality rate of post-transplantation pancreatitis, as determined from our review of the literature of the last 15 years, are 2·3 and 61·3 per cent, respectively; these are similar to the figures found up to 1970 of 1·7 and 52·2 per cent. A multiplicity of factors present in the uraemic patient may be responsible for the continued frequency of post-transplant pancreatitis despite advances in surgical technique and immunosuppressive therapy.Keywords
This publication has 16 references indexed in Scilit:
- Hypercalcemia associated with pancreatitis and hyperamylasemia in renal transplant recipientsThe American Journal of Surgery, 1987
- TOXIC EFFECTS OF CYCLOSPORINE ON THE ENDOCRINE PANCREAS OF WISTAR RATSTransplantation, 1985
- Acute Pancreatitis following Renal TransplantationDigestive Surgery, 1985
- DETERIORATION IN GLUCOSE METABOLISM IN PANCREATIC TRANSPLANT RECIPIENTS GIVEN CYCLOSPORINThe Lancet, 1983
- Gastrointestinal and pancreatic complications after kidney transplantationInternational Urology and Nephrology, 1983
- Cytomegalovirus Disease in Renal Allograft RecipientsMedicine, 1980
- Acute pancreatitis following renal allotransplantationDigestive Diseases and Sciences, 1978
- Gastrointestinal and hepatic complications affecting patients with renal allograftsThe American Journal of Surgery, 1975
- Pancreatitis after renal transplantationThe American Journal of Surgery, 1972
- Pancreatitis in Renal TransplantationAnnals of Surgery, 1970