EXPERIMENTAL INVESTIGATION OF THE VALUE OF THE VARIOUS COMMERCIAL OVARIAN EXTRACTS*

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Abstract
Much has been done and written on the therapeutic value of the numerous endocrine preparations, but unfortunately, most of the work is empirical in nature. While it is true that many valuable facts have been acquired in this way, still it seems that the mass of evidence is based on the interpretations of the investigators and the statements of the patients, which statements may be influenced psychically. It would be much more advantageous if we could experimentally demonstrate the clinical value or a definite physiological activity of the commercial endocrine products, and be able at any time to duplicate the results. There are many objections to the empirical method in addition to those mentioned above, for we know that it is extremely difficult at the present time to classify accurately the various types of endocrinological syndromes, with few exceptions, and in addition, the overlapping of groups makes the results of investigation more uncertain.

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