Clinical Pharmacology of Levosimendan
- 1 January 2007
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 46 (7) , 535-552
- https://doi.org/10.2165/00003088-200746070-00001
Abstract
Levosimendan has been developed for the treatment of decompensated heart failure and is used intravenously when patients with heart failure require immediate initiation of drug therapy. It increases...Keywords
This publication has 70 references indexed in Scilit:
- Peripartum cardiomyopathy: A new successful setting for levosimendanInternational Journal of Cardiology, 2008
- Effect of Severe Renal Failure and Haemodialysis on the Pharmacokinetics of Levosimendan and Its MetabolitesClinical Pharmacokinetics, 2007
- Effect of Levosimendan on Ventricular Arrhythmias and Prognostic Autonomic Indexes in Patients With Decompensated Advanced Heart Failure Secondary to Ischemic or Dilated CardiomyopathyThe American Journal of Cardiology, 2006
- Levosimendan improves hemodynamics and coronary flow reserve after percutaneous coronary intervention in patients with acute myocardial infarction and left ventricular dysfunctionAmerican Heart Journal, 2005
- Effects of Levosimendan on Markers of Left Ventricular Diastolic Function and Neurohormonal Activation in Patients With Advanced Heart FailureThe American Journal of Cardiology, 2005
- Levosimendan reduces plasma B-type natriuretic peptide and interleukin 6, and improves central hemodynamics in severe heart failure patientsInternational Journal of Cardiology, 2005
- Pharmacodynamics and Pharmacokinetics of Oral Levosimendan and Its Metabolites in Patients With Severe Congestive Heart Failure: A Dosing Interval StudyThe Journal of Clinical Pharmacology, 2004
- Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failureThe American Journal of Cardiology, 2004
- Pharmacokinetics and Pharmacodynamics of Intravenous Inotropic AgentsClinical Pharmacokinetics, 2004
- Pharmacokinetic-pharmacodynamic interrelationships of intravenous and oral levosimendan in patients with severe congestive heart failureInt. Journal of Clinical Pharmacology and Therapeutics, 2003