Inactivation of p53 and Amplification of Cyclin D1 Correlate With Clinical Outcome in Head and Neck Cancer
- 1 March 1998
- journal article
- research article
- Published by Wiley in The Laryngoscope
- Vol. 108 (3) , 345-350
- https://doi.org/10.1097/00005537-199803000-00007
Abstract
The authors have investigated whether genetic abnormalities in two genes, loss of heterozygosity (LOH) of p53 and amplification of the cyclin D1 gene, correlate with clinical outcome in 56 matched pa...Keywords
This publication has 10 references indexed in Scilit:
- Association between Cigarette Smoking and Mutation of the p53 Gene in Squamous-Cell Carcinoma of the Head and NeckNew England Journal of Medicine, 1995
- Allelic Loss at Chromosomes 3p, 8p, 13q, and l7p Associated With Poor Prognosis in Head and Neck CancerJNCI Journal of the National Cancer Institute, 1994
- PRAD-1 (CCND1)/Cyclin D1 oncogene amplification in primary head and neck squamous cell carcinomaCancer, 1994
- Chromosome 11Q13 Amplification in Head and Neck Squamous Cell CarcinomaJAMA Otolaryngology–Head & Neck Surgery, 1993
- The Role of the p53 Tumor Suppressor Gene in Squamous Cell Carcinoma of the Head and NeckJAMA Otolaryngology–Head & Neck Surgery, 1993
- Polymerase chain reaction detection of a highly polymorphic VNTR segment in intron 1 of the human p53 geneClinical Chemistry, 1993
- A novel cyclin encoded by a bcl1-linked candidate oncogeneNature, 1991
- Accll polymorphism of the p53 geneNucleic Acids Research, 1990
- Genetic Alterations during Colorectal-Tumor DevelopmentNew England Journal of Medicine, 1988