The effects of tibolone
- 1 January 1998
- journal article
- review article
- Published by Taylor & Francis in Gynecological Endocrinology
- Vol. 12 (3) , 213-220
- https://doi.org/10.3109/09513599809015548
Abstract
Tibolone is a non-bleeding form of hormone replacement therapy (HRT). When ingested, it is broken down into metabolites, of which the progestogenic metabolite predominates at the level of the endometrium, so that an atrophic endometrium is produced. For the postmenopausal woman, the availability of non-bleeding HRT has great appeal, and compliance is substantially improved. Other clinical situations in which tibolone is particularly useful include: women who have had hormone-dependent tumors in the past, women who have had endometriosis and women taking gonadotropin-releasing hormone agonists.Keywords
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