Ca2+ Dependent Phosphorylation of Bovine Aortic Actomyosin
- 1 July 1978
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 158 (3) , 410-414
- https://doi.org/10.3181/00379727-158-40215
Abstract
Studies of bovine aortic actomyosin employing isoelectric focusing and sodium dodecyl sulfate electrophoresis demonstrated Ca2+ dependent phosphorylation of 15,000 dalton polypeptides. Polypeptides probably correspond to the myosin L chains. The Ca2+ requirement for phosphorylation parallels the Ca2+ requirement for activation of Mg2+ stimulated actomyosin ATPase. Findings suggest that the Ca2+ regulatory mechanism for actin-myosin interactions in mammalian vascular smooth muscle may be partly mediated by phosphorylation of myosin L chains.This publication has 8 references indexed in Scilit:
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