Beta-adrenergic receptor function in affective illness
- 1 May 1979
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 136 (5) , 675-678
- https://doi.org/10.1176/ajp.136.5.675
Abstract
The response of cyclic[c]AMP synthesis to in vitro addition of norepinephrine and isoproterenol (IP) was determined in leukocytes of patients with affective illness and schizophrenia and of normal controls. IP-stimulated increase in 3H-cAMP synthesis in depressed patients was significantly lower than in normal subjects and schizophrenic patients. .beta.-adrenergic receptor sensitivity is apparently reduced in depressive illness.This publication has 4 references indexed in Scilit:
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