Towards the prevention of neural tube defects

1 November 1989

journal article
review article
Published by Wiley in Clinical Genetics

Vol. 36 (5) , 339-347
https://doi.org/10.1111/j.1399-0004.1989.tb03211.x

Abstract

The value of maternal periconceptional vitamin supplementation in preventing the conception of fetuses with neural tube defects has yet to be assessed in a properly designed study. Avoidance of the birth of affected infants continues to rest on second‐trimester maternal serum alphafetoprotein screening. The performance of screening programmes in achieving this objective is reviewed.

Keywords

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