HIGH DOSE, PREOPERATIVE SUPERVOLTAGE IRRADIATION FOR OSTEOGENIC SARCOMA

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Abstract
A series of 17 cases with biopsy proven osteogenic sarcoma of an extremity from the National Naval Medical Center, Bethesda, Maryland, and the Medical College of Virginia, Richmond, Virginia, over a 15 year period (1955-1969) were treated with preoperative irradiation to doses of 6,000-8,600 rads followed by amputation or disarticulation of the extremity in the majority of cases. A brief review of the literature regarding treatment of osteogenic sarcoma is undertaken, with attention on the quality and duration of survival. Because our experience confirms the results obtained in other studies, we believe that the combined approach in the management of the patient with osteogenic sarcoma offers a better chance of survival and is a more rational approach than any single modality available at this time.

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