Control of Chemotherapy-Induced Emesis

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Abstract
Chemotherapy regimens for the treatment of cancer are unfortunately better known for their toxicity than for their efficacy. Although some of the toxic effects may be life-threatening, patients are often most fearful of the nausea and emesis caused by chemotherapy, which are generally self-limited and seldom life-threatening1. Effective control of nausea and emesis is therefore a central goal of physicians using chemotherapy regimens.Treatment of emesis in a patient with cancer begins with an evaluation of the possible causes. Physical complications of cancer (a brain metastasis or bowel obstruction), metabolic complications (hypercalcemia), or unrelated factors (a gastric ulcer or . . .