Modifications of primaquine as antimalarials. 1. 5-Phenoxy derivatives of primaquine
- 1 August 1977
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 20 (8) , 1107-1109
- https://doi.org/10.1021/jm00218a026
Abstract
Various 5-phenoxy derivatives of primaquine were prepared which are more active and less toxic than the parent compound in murine and monkey antimalarial screens. An improved method for the phthalimido alkylation of amines is described.This publication has 1 reference indexed in Scilit:
- 2,4,7-Triamino-6-ortho-substituted Arylpteridines. A New Series of Potent Antimalarial AgentsJournal of Medicinal Chemistry, 1967