Off‐Signals in Lymphocyte Activation
- 1 May 1976
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 5 (5) , 583-586
- https://doi.org/10.1111/j.1365-3083.1976.tb00313.x
Abstract
High-dose unresponsiveness to concanavalin A [Con A] affected T [thymus-derived] and B [bone marrow-derived] lymphocytes [mouse] equally, although only T cells were activated by Con A. Activation and inactivation signals are totally unrelated, the latter also lacking target cell specificity. The off-signal caused cell death and is probably biologically unimportant.This publication has 6 references indexed in Scilit:
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- Selective induction of DNA synthesis in T and B lymphocytesCellular Immunology, 1972