The Non-cyclooxygenase Targets of Non-steroidal Anti-inflammatory Drugs, Lipoxygenases, Peroxisome Proliferator-activated Receptor, Inhibitor of κB Kinase, and NFκB, Do Not Reduce Amyloid β42 Production
Open Access
- 1 August 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (34) , 31825-31830
- https://doi.org/10.1074/jbc.m303588200
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidenceNeurobiology of Aging, 2001
- A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activityNature, 2001
- Presenilin 1 Regulates Pharmacologically Distinct γ-Secretase ActivitiesJournal of Biological Chemistry, 2000
- PDZ Domain-dependent Suppression of NF-κB/p65-induced Aβ42 Production by a Neuron-specific X11-like ProteinJournal of Biological Chemistry, 2000
- Sulindac Inhibits Activation of the NF-κB PathwayJournal of Biological Chemistry, 1999
- Nonsteroidal Anti-Inflammatory Drugs as Scaffolds for the Design of 5-Lipoxygenase InhibitorsJournal of Medicinal Chemistry, 1997
- Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory DrugsJournal of Biological Chemistry, 1997
- Improved electrophoretic separation and immunoblotting of beta‐amyloid (Aβ) peptides 1–40, 1–42, and 1–43Electrophoresis, 1997
- Phospholipase A2 Activation Influences the Processing and Secretion of the Amyloid Precursor ProteinBiochemical and Biophysical Research Communications, 1993
- Nonsteroidal anti-inflammatory drugs stimulate 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytesJournal of Allergy and Clinical Immunology, 1984