PRENYLAMINE IN ANGINA PECTORIS

  • 1 January 1963
    • journal article
    • research article
    • Vol. 89  (6) , 248-+
Abstract
The therapeutic value of prenylamine in angina pectoris was tested in 2 ways. Fourteen patients received 270 mg of prenylamine/day for 1 month. This was preceded and followed by 1 month of placebo therapy. Assessment was made, first by twice-monthly treadmill exercise tests, and secondly by daily records of anginal attacks and nitroglycerin usage. The occurrence of pain and ecg changes during treadmill exercise was apparently uninfluenced by the drug. However, there was a reduced incidence of spontaneous angina and nitroglycerin usage during the month on prenylamine by contrast with either month on placebo (p< 0.05).