Selective Association of Cholesterol with Long-Chain Phospholipids in Liquid-Ordered Bilayers: Support for the Existence of Lipid Rafts
- 1 October 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (43) , 13040-13041
- https://doi.org/10.1021/ja038102n
Abstract
Nearest-neighbor recognition experiments, which have been carried out under fluidizing and condensing conditions, using exchangeable dimers derived from 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, and cholesterol, have provided strong evidence that sterol-phospholipid recognition is limited to the liquid-ordered phase.Keywords
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