MDM2 interacts with MDMX through their RING finger domains
Open Access
- 19 March 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 447 (1) , 5-9
- https://doi.org/10.1016/s0014-5793(99)00254-9
Abstract
The N‐terminus of MDM2 proto‐oncoprotein interacts with p53 and down modulates p53 activity by inhibiting transcriptional activity and promoting p53 degradation. MDMX is structurally related to MDM2 ...Keywords
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