Primary Carcinoma of the Female Urethra

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Abstract
The clinical and morphological features in 81 cases of carcinoma of the female urethra were reviewed. The over-all 5 and 10 yr survival rate for the entire group was 32%. Survival expectations for patients with squamous carcinoma, transitional cell carcinoma and adenocarcinoma were similar when analyzed according to stage and all cell types appeared to respond equally to irradiation. Prognosis was related directly to the clinical stage of the disease. A plea is made for more accurate assessment of the disease status. The high incidence of local recurrence noted for all forms of single modality therapy (46-64%) suggests the need for clinical trials with combination preoperative irradiation followed by definitive surgical procedures.

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