The Membrane Potential of Resting and Activated Neutrophils: Determinants and Significance
- 1 January 1991
- journal article
- review article
- Published by S. Karger AG in Cellular Physiology and Biochemistry
- Vol. 1 (2) , 65-75
- https://doi.org/10.1159/000154595
Abstract
When activated, neutrophils display a number of biological responses, including chemotaxis, exocytosis and a respiratory burst. Concomitantly, these cells undergo marked changes in their transmembrane potential. The purpose of this brief manuscript is to critically review the existing information regarding the determinants of the resting membrane potential of neutrophils and the mechanisms proposed to underlie the depolarization recorded upon activation. In addition, the possible functional significance of the membrane potential changes is also discussed succinctly.Keywords
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