Balancing benefits and harms in health care: Observational data on harm are already included in systematic reviews

Abstract
# Observational data on harm are already included in systematic reviews {#article-title-2} EDITOR–The correspondence on the issue of including observational data of harm in systematic reviews surprised us.1 2 The tone of the prose implied that this might happen in the future, and the limits of randomised controlled trials discussed told readers what anyone working in assessing adverse events knows only too well. Observational data have been included in systematic …