The Synthesis of Oligonucleotides Containing Fluoro-2′-Deoxycytidine for Secondary Structure Determination of Tandem Tetraloop DNA Analogs
- 1 October 1997
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 16 (10-11) , 1809-1820
- https://doi.org/10.1080/07328319708002535
Abstract
A method to convert 5-FdU phosphoramidite to 4-triazol-5- FdU phosphoramidite was used to make deoxyoligonucleotides containing 5- FdC to follow a rare transition between a tandem hairpin and a single hairpin form, which results in moving a distant 5-FdC, 5-FdU bases into juxtaposition.Keywords
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